Bio

I am a cardiovascular scientist and physician-scientist with extensive international research experience across China, Europe, and the United States, and advanced training in molecular cardiology, cardiac immunology, and translational cardiovascular research. My work focuses on understanding the cellular and molecular mechanisms that drive cardiac injury, repair, and valve disease, with the long-term goal of translating mechanistic insights into new therapeutic strategies.

I received my MD from Belarusian State Medical University, followed by advanced clinical training in anesthesiology and intensive care. I later completed an MS in Surgery at Shanghai Jiao Tong University and earned my PhD in Cell Biology/Molecular Cardiology from the Chinese Academy of Sciences, where my doctoral research focused on immune responses and myocardial injury in clinically relevant animal models. 

My postdoctoral training spans leading international research institutions. I began my research postdoctoral fellowship at INSERM at the Institute of Biology Valrose (iBV), where I further developed expertise in cardiovascular and inflammatory disease mechanisms. I subsequently completed an Immunopathology Fellowship at Johns Hopkins University, where I developed novel murine models of cardiovascular injury and investigated the roles of innate and adaptive immune cells in myocardial infarction, ischemia–reperfusion injury, and pericardial biology. I later joined the Division of Cardiology at Children’s Hospital of Philadelphia (CHOP) as an NIH T32 Cardiology Fellow, where my work centered on mitral valve biology, mechanosensing, and serotonin-dependent signaling pathways, including the role of mechanosensitive ion channels PIEZO1 and PIEZO2 in valve pathophysiology.

Throughout my training, I have developed a deep expertise in preclinical cardiovascular models, including closed- and open-chest mouse models of myocardial infarction, abdominal aortic aneurysm, and drug-induced mitral valvopathy, as well as swine models of ischemia–reperfusion injury.

My technical background includes mouse microsurgery, echocardiography, flow cytometry, single-cell and molecular analyses, histopathology, and advanced imaging, enabling fully integrated mechanistic studies from molecule to organ level. In parallel with research, I am deeply committed to teaching and mentorship. I have trained undergraduate students, graduate students, postdoctoral fellows, and physician-scientists, emphasizing rigorous experimental design, hands-on technical training, and critical scientific thinking.

My teaching interests include fundamentals of cardiology, molecular cardiology, and cardiac immunology. Through my work, I aim to bridge basic discovery and translational impact, advancing our understanding of cardiovascular disease mechanisms and contributing to the development of innovative therapies for patients with heart and valve disease.